Texas Tech University Health Sciences Center
New Research to Examine Effects of Vitamin E on Obesity

New Research to Examine Effects of Vitamin E on Obesity

Dr. Shen

Of the 13 essential vitamins, vitamin E is known to benefit vision, reproduction and a person’s blood, brain and skin. Researchers at Texas Tech University Health Sciences Center (TTUHSC) now are studying vitamin E to examine the effects of the vitamin on obesity with postmenopausal women.

Vitamin E has antioxidant properties that protect cells against molecules produced when your body breaks down food. Leslie Shen, Ph.D., a TTUHSC professor in the Department of Pathology, said these molecules may play a role in other diseases such as obesity.

“Postmenopausal women are at a risk of excessive weight gain, bone loss, hypertension and metabolic syndrome,”Shen said. “Among these risk factors, obesity is now recognized as a worldwide epidemic disease. Obesity-induced chronic low-grade inflammation is initiated by excess nutrients in metabolic cells.”

Shen said aging and the decline of estrogen are factors that contribute to weight gain in postmenopausal women, and approaches, such as anti-inflammatory potential in dietary antioxidants to reduce inflammation may likely combat obesity. TTUHSC researchers are conducting a 24-week research study examining the effects of tocotrienols, a type of vitamin E, on obesity-associated outcome measures in postmenopausal women.

Participants are needed for this study, “Effect of Tocotrienol (vitamin E isomers) on Obesity.” Shen said other studies have indicated tocotrienols supplements may be good for mitigating negative impacts of obesity in postmenopausal women.

“However, no study has ever been done on the role of tocotrienols in obesity in postmenopausal women,” Shen said. “Our long-term goal is to develop a new strategy featuring a dietary supplement such as tocotrienols for mitigating negative impacts of obesity in postmenopausal women.”

Participants should be postmenopausal women (at least one year after menopause). Participation is free of charge. The study is funded by a grant from School of Medicine, TTUHSC and the Laura W. Bush Institute for Women’s Health.  

For more information about this research study, contact Anna Rodriguez at (806) 743-2533 or anna.rodriguez@ttuhsc.edu.